Tyrosine Phosphorylation of Mitochondrial Creatine Kinase 1 Enhances a Druggable Tumor Energy Shuttle Pathway. [electronic resource]
- Cell metabolism 12 2018
- 833-847.e8 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
1932-7420
10.1016/j.cmet.2018.08.008 doi
Animals Antineoplastic Agents--therapeutic use Antineoplastic Combined Chemotherapy Protocols--therapeutic use Breast Neoplasms--metabolism Cell Line, Tumor Cell Transformation, Neoplastic Creatine Kinase--genetics Creatinine--analogs & derivatives Drug Resistance, Neoplasm Energy Metabolism Energy Transfer Female Gene Knockdown Techniques Humans Lapatinib--therapeutic use Mice Mice, Nude Mitochondria--metabolism Mitochondrial Proteins--metabolism Phosphocreatine--metabolism Phosphorylation Receptor, ErbB-2--metabolism Trastuzumab--therapeutic use Xenograft Model Antitumor Assays