Ye, Dan <br/><br/>
A pore-localizing CACNA1C-E1115K missense mutation, identified in a patient with idiopathic QT prolongation, bradycardia, and autism spectrum disorder, converts the L-type calcium channel into a hybrid nonselective monovalent cation channel.  [electronic resource] 

 -  Heart rhythm  02 2019 
 - 270-278 p.  digital 
<br/><br/> Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1556-3871 
<br/><br/><label>Standard No.: </label>10.1016/j.hrthm.2018.08.030  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adolescent<br/>Autism Spectrum Disorder--genetics<br/>Bradycardia--diagnosis<br/>Calcium Channels, L-Type--genetics<br/>Cells, Cultured<br/>DNA--genetics<br/>DNA Mutational Analysis<br/>Electrocardiography<br/>Humans<br/>Male<br/>Mutation, Missense<br/>Patch-Clamp Techniques<br/>Pedigree<br/>Romano-Ward Syndrome--diagnosis