TY - GEN AU - King,Andrew J AU - Siegel,Matthew AU - He,Ying AU - Nie,Baoming AU - Wang,Ji AU - Koo-McCoy,Samantha AU - Minassian,Natali A AU - Jafri,Qumber AU - Pan,Deng AU - Kohler,Jill AU - Kumaraswamy,Padmapriya AU - Kozuka,Kenji AU - Lewis,Jason G AU - Dragoli,Dean AU - Rosenbaum,David P AU - O'Neill,Debbie AU - Plain,Allein AU - Greasley,Peter J AU - Jönsson-Rylander,Ann-Cathrine AU - Karlsson,Daniel AU - Behrendt,Margareta AU - Strömstedt,Maria AU - Ryden-Bergsten,Tina AU - Knöpfel,Thomas AU - Pastor Arroyo,Eva M AU - Hernando,Nati AU - Marks,Joanne AU - Donowitz,Mark AU - Wagner,Carsten A AU - Alexander,R Todd AU - Caldwell,Jeremy S TI - Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability SN - 1946-6242 PY - 2019///1011 KW - Adult KW - Aged KW - Animals KW - Base Sequence KW - Cell Membrane Permeability KW - drug effects KW - Cells, Cultured KW - Electric Impedance KW - Epithelium KW - metabolism KW - Female KW - Gastrointestinal Tract KW - Healthy Volunteers KW - Humans KW - Hydrogen-Ion Concentration KW - Intestinal Absorption KW - Ions KW - urine KW - Isoquinolines KW - pharmacology KW - Male KW - Mice KW - Middle Aged KW - Phosphates KW - Potassium KW - Protons KW - Rats KW - Sodium KW - Sodium-Hydrogen Exchanger 3 KW - antagonists & inhibitors KW - Sulfonamides KW - Tight Junction Proteins KW - Young Adult N1 - Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1126/scitranslmed.aam6474 ER -