King, Andrew J <br/><br/>
Inhibition of sodium/hydrogen exchanger 3 in the gastrointestinal tract by tenapanor reduces paracellular phosphate permeability.  [electronic resource] 

 -  Science translational medicine  08 2018 
<br/><br/> Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1946-6242 
<br/><br/><label>Standard No.: </label>10.1126/scitranslmed.aam6474  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adult<br/>Aged<br/>Animals<br/>Base Sequence<br/>Cell Membrane Permeability--drug effects<br/>Cells, Cultured<br/>Electric Impedance<br/>Epithelium--metabolism<br/>Female<br/>Gastrointestinal Tract--metabolism<br/>Healthy Volunteers<br/>Humans<br/>Hydrogen-Ion Concentration<br/>Intestinal Absorption--drug effects<br/>Ions--urine<br/>Isoquinolines--pharmacology<br/>Male<br/>Mice<br/>Middle Aged<br/>Phosphates--metabolism<br/>Potassium--metabolism<br/>Protons<br/>Rats<br/>Sodium--metabolism<br/>Sodium-Hydrogen Exchanger 3--antagonists & inhibitors<br/>Sulfonamides--pharmacology<br/>Tight Junction Proteins--metabolism<br/>Young Adult