TY - GEN AU - Liu,Ta-Chiang AU - Kern,Justin T AU - VanDussen,Kelli L AU - Xiong,Shanshan AU - Kaiko,Gerard E AU - Wilen,Craig B AU - Rajala,Michael W AU - Caruso,Roberta AU - Holtzman,Michael J AU - Gao,Feng AU - McGovern,Dermot Pb AU - Nunez,Gabriel AU - Head,Richard D AU - Stappenbeck,Thaddeus S TI - Interaction between smoking and ATG16L1T300A triggers Paneth cell defects in Crohn's disease SN - 1558-8238 PY - 2019///0911 KW - Animals KW - Apoptosis KW - drug effects KW - Autophagy-Related Proteins KW - genetics KW - Carrier Proteins KW - Crohn Disease KW - Female KW - Genetic Predisposition to Disease KW - Humans KW - Male KW - Mice KW - Mice, Knockout KW - Mutation, Missense KW - PPAR gamma KW - Paneth Cells KW - metabolism KW - Rosiglitazone KW - pharmacology KW - Smoking N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1172/JCI120453 ER -