Fenini, Gabriele <br/><br/>
Genome Editing of Human Primary Keratinocytes by CRISPR/Cas9 Reveals an Essential Role of the NLRP1 Inflammasome in UVB Sensing.  [electronic resource] 

 -  The Journal of investigative dermatology  12 2018 
 - 2644-2652 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1523-1747 
<br/><br/><label>Standard No.: </label>10.1016/j.jid.2018.07.016  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adaptor Proteins, Signal Transducing--metabolism<br/>Apoptosis Regulatory Proteins--metabolism<br/>CRISPR-Associated Protein 9--genetics<br/>CRISPR-Cas Systems<br/>Cells, Cultured<br/>Gene Editing--methods<br/>Humans<br/>Inflammasomes--metabolism<br/>Interleukin-18--metabolism<br/>Interleukin-1beta--metabolism<br/>Keratinocytes--physiology<br/>NLR Family, Pyrin Domain-Containing 3 Protein--metabolism<br/>NLR Proteins<br/>Nigericin--pharmacology<br/>Primary Cell Culture<br/>Radiodermatitis--genetics<br/>Ultraviolet Rays--adverse effects