TY  - GEN
AU  - Rashid,Masturah Bte Mohd Abdul
AU  - Toh,Tan Boon
AU  - Hooi,Lissa
AU  - Silva,Aleidy
AU  - Zhang,Yanzhou
AU  - Tan,Pei Fang
AU  - Teh,Ai Ling
AU  - Karnani,Neerja
AU  - Jha,Sudhakar
AU  - Ho,Chih-Ming
AU  - Chng,Wee Joo
AU  - Ho,Dean
AU  - Chow,Edward Kai-Hua
TI  - Optimizing drug combinations against multiple myeloma using a quadratic phenotypic optimization platform (QPOP)
SN  - 1946-6242
PY  - 2019///1011
KW  - Animals
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - pharmacology
KW  - Bortezomib
KW  - Cell Line, Tumor
KW  - Cyclin-Dependent Kinase Inhibitor p21
KW  - genetics
KW  - DNA Damage
KW  - DNA Methylation
KW  - Decitabine
KW  - Dose-Response Relationship, Drug
KW  - Drug Resistance, Neoplasm
KW  - drug effects
KW  - Drug Synergism
KW  - Gene Expression Regulation, Neoplastic
KW  - Genes, Tumor Suppressor
KW  - High-Throughput Screening Assays
KW  - Humans
KW  - Mice
KW  - Mitomycin
KW  - Multiple Myeloma
KW  - drug therapy
KW  - Phenotype
KW  - Protein Tyrosine Phosphatase, Non-Receptor Type 6
KW  - RNA, Messenger
KW  - Tumor Burden
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S
UR  - https://doi.org/10.1126/scitranslmed.aan0941
ER  -