Wang, Zhen <br/><br/>
Design, Synthesis, and Biological Evaluation of 3-(Imidazo[1,2- a]pyrazin-3-ylethynyl)-4-isopropyl- N-(3-((4-methylpiperazin-1-yl)methyl)-5-(trifluoromethyl)phenyl)benzamide as a Dual Inhibitor of Discoidin Domain Receptors 1 and 2.  [electronic resource] 

 -  Journal of medicinal chemistry  09 2018 
 - 7977-7990 p.  digital 
<br/><br/> Publication Type: Evaluation Study; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1520-4804 
<br/><br/><label>Standard No.: </label>10.1021/acs.jmedchem.8b01045  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Acute Lung Injury--chemically induced<br/>Animals<br/>Anti-Inflammatory Agents--chemical synthesis<br/>Discoidin Domain Receptor 1--antagonists & inhibitors<br/>Discoidin Domain Receptor 2--antagonists & inhibitors<br/>Drug Design<br/>Humans<br/>Lipopolysaccharides--toxicity<br/>Male<br/>Mice<br/>Mice, Inbred C57BL<br/>Pneumonia--chemically induced<br/>Rats<br/>Rats, Sprague-Dawley