Berberine ameliorates blockade of autophagic flux in the liver by regulating cholesterol metabolism and inhibiting COX2-prostaglandin synthesis. [electronic resource]
- Cell death & disease 08 2018
- 824 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2041-4889
10.1038/s41419-018-0890-5 doi
Animals Autophagy--drug effects Berberine--pharmacology Cholesterol--metabolism Cyclooxygenase 2--chemistry Diet, High-Fat Hep G2 Cells Humans Liver--drug effects Male Mice Microtubule-Associated Proteins--genetics Phosphorylation--drug effects Prostaglandins--metabolism Proto-Oncogene Proteins c-akt--metabolism Sequestosome-1 Protein--metabolism TOR Serine-Threonine Kinases--metabolism