17β-Estradiol inhibits testosterone-induced cell proliferation in HepG2 by modulating the relative ratios of 3 estrogen receptor isoforms to the androgen receptor. [electronic resource]
- Journal of cellular biochemistry 11 2018
- 8659-8671 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1097-4644
10.1002/jcb.27111 doi
Analysis of Variance Apoptosis--drug effects Carcinoma, Hepatocellular--metabolism Cell Cycle Checkpoints--drug effects Cell Proliferation--drug effects Cell Survival--drug effects Estradiol--pharmacology Estrogen Receptor alpha Estrogens--pharmacology Hep G2 Cells Humans Liver Neoplasms--metabolism Male Protein Isoforms--metabolism RNA, Messenger--metabolism Receptors, Androgen--metabolism Receptors, Estrogen--metabolism Signal Transduction--drug effects Testosterone--pharmacology