TY - GEN AU - Qiu,Hong AU - Zmina,Patrick M AU - Huang,Alex Y AU - Askew,David AU - Bedogni,Barbara TI - Inhibiting Notch1 enhances immunotherapy efficacy in melanoma by preventing Notch1 dependent immune suppressive properties SN - 1872-7980 PY - 2019///0930 KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - pharmacology KW - CD8-Positive T-Lymphocytes KW - immunology KW - Cell Line, Tumor KW - Cytokines KW - genetics KW - Female KW - Humans KW - Immunotherapy KW - methods KW - Ipilimumab KW - administration & dosage KW - Melanoma, Experimental KW - Mice, Inbred C57BL KW - Myeloid-Derived Suppressor Cells KW - Nivolumab KW - RNA Interference KW - Receptor, Notch1 KW - T-Lymphocytes, Regulatory KW - Treatment Outcome KW - Tumor Burden KW - drug effects KW - Tumor Microenvironment N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural UR - https://doi.org/10.1016/j.canlet.2018.07.024 ER -