Qiu, Hong

Inhibiting Notch1 enhances immunotherapy efficacy in melanoma by preventing Notch1 dependent immune suppressive properties. [electronic resource] - Cancer letters 10 2018 - 144-151 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural

1872-7980

10.1016/j.canlet.2018.07.024 doi


Animals
Antineoplastic Combined Chemotherapy Protocols--pharmacology
CD8-Positive T-Lymphocytes--immunology
Cell Line, Tumor
Cytokines--genetics
Female
Humans
Immunotherapy--methods
Ipilimumab--administration & dosage
Melanoma, Experimental--genetics
Mice, Inbred C57BL
Myeloid-Derived Suppressor Cells--immunology
Nivolumab--administration & dosage
RNA Interference
Receptor, Notch1--genetics
T-Lymphocytes, Regulatory--immunology
Treatment Outcome
Tumor Burden--drug effects
Tumor Microenvironment--drug effects