TY - GEN AU - Chen,Haiyan AU - Lu,An AU - Zhang,Xiaoyi AU - Gui,Lin AU - Wang,Yaonan AU - Wu,Jianhui AU - Feng,Hua AU - Peng,Shiqi AU - Zhao,Ming TI - Design and development of ICCA as a dual inhibitor of GPIIb/IIIa and P-selectin receptors SN - 1177-8881 PY - 2018///1211 KW - Animals KW - Antibiotics, Antineoplastic KW - chemical synthesis KW - Carbolines KW - Cell Line, Tumor KW - Cell Proliferation KW - drug effects KW - Dose-Response Relationship, Drug KW - Down-Regulation KW - Doxorubicin KW - Drug Design KW - Drug Screening Assays, Antitumor KW - Humans KW - Male KW - Mice KW - Mice, Inbred ICR KW - Models, Molecular KW - Molecular Structure KW - Neoplasms, Experimental KW - drug therapy KW - P-Selectin KW - antagonists & inhibitors KW - Platelet Aggregation KW - Platelet Aggregation Inhibitors KW - Platelet Glycoprotein GPIIb-IIIa Complex KW - Rats KW - Rats, Sprague-Dawley KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.2147/DDDT.S169238 ER -