Chen, Haiyan
Design and development of ICCA as a dual inhibitor of GPIIb/IIIa and P-selectin receptors. [electronic resource]
- Drug design, development and therapy 2018
- 2097-2110 p. digital
Publication Type: Journal Article
ISSN: 1177-8881
Standard No.: 10.2147/DDDT.S169238 doi
Subjects--Topical Terms: Animals Antibiotics, Antineoplastic--chemical synthesis Carbolines--chemical synthesis Cell Line, Tumor Cell Proliferation--drug effects Dose-Response Relationship, Drug Down-Regulation--drug effects Doxorubicin--chemical synthesis Drug Design Drug Screening Assays, Antitumor Humans Male Mice Mice, Inbred ICR Models, Molecular Molecular Structure Neoplasms, Experimental--drug therapy P-Selectin--antagonists & inhibitors Platelet Aggregation--drug effects Platelet Aggregation Inhibitors--chemical synthesis Platelet Glycoprotein GPIIb-IIIa Complex--antagonists & inhibitors Rats Rats, Sprague-Dawley Structure-Activity Relationship