Chen, Haiyan

Design and development of ICCA as a dual inhibitor of GPIIb/IIIa and P-selectin receptors. [electronic resource] - Drug design, development and therapy 2018 - 2097-2110 p. digital

Publication Type: Journal Article

1177-8881

10.2147/DDDT.S169238 doi


Animals
Antibiotics, Antineoplastic--chemical synthesis
Carbolines--chemical synthesis
Cell Line, Tumor
Cell Proliferation--drug effects
Dose-Response Relationship, Drug
Down-Regulation--drug effects
Doxorubicin--chemical synthesis
Drug Design
Drug Screening Assays, Antitumor
Humans
Male
Mice
Mice, Inbred ICR
Models, Molecular
Molecular Structure
Neoplasms, Experimental--drug therapy
P-Selectin--antagonists & inhibitors
Platelet Aggregation--drug effects
Platelet Aggregation Inhibitors--chemical synthesis
Platelet Glycoprotein GPIIb-IIIa Complex--antagonists & inhibitors
Rats
Rats, Sprague-Dawley
Structure-Activity Relationship