TY - GEN AU - Wang,Zhijie AU - Cheng,Ying AU - An,Tongtong AU - Gao,Hongjun AU - Wang,Kai AU - Zhou,Qing AU - Hu,Yanping AU - Song,Yong AU - Ding,Cuimin AU - Peng,Feng AU - Liang,Li AU - Hu,Yi AU - Huang,Cheng AU - Zhou,Caicun AU - Shi,Yuankai AU - Zhang,Li AU - Ye,Xin AU - Zhang,Meizhuo AU - Chuai,Shaokun AU - Zhu,Guanshan AU - Hu,Jin AU - Wu,Yi-Long AU - Wang,Jie TI - Detection of EGFR mutations in plasma circulating tumour DNA as a selection criterion for first-line gefitinib treatment in patients with advanced lung adenocarcinoma (BENEFIT): a phase 2, single-arm, multicentre clinical trial SN - 2213-2619 PY - 2019///0531 KW - Adenocarcinoma KW - drug therapy KW - Administration, Oral KW - Adult KW - Aged KW - Biomarkers, Tumor KW - blood KW - Circulating Tumor DNA KW - DNA Mutational Analysis KW - methods KW - Disease-Free Survival KW - Female KW - Gefitinib KW - administration & dosage KW - Genes, Tumor Suppressor KW - Genes, erbB-1 KW - Humans KW - Intention to Treat Analysis KW - Lung Neoplasms KW - Male KW - Middle Aged KW - Mutation KW - Protein Kinase Inhibitors KW - Sensitivity and Specificity N1 - Publication Type: Clinical Trial, Phase II; Journal Article; Multicenter Study; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/S2213-2600(18)30264-9 ER -