TY  - GEN
AU  - Kundu,Samrat T
AU  - Grzeskowiak,Caitlin L
AU  - Fradette,Jared J
AU  - Gibson,Laura A
AU  - Rodriguez,Leticia B
AU  - Creighton,Chad J
AU  - Scott,Kenneth L
AU  - Gibbons,Don L
TI  - TMEM106B drives lung cancer metastasis by inducing TFEB-dependent lysosome synthesis and secretion of cathepsins
SN  - 2041-1723
PY  - 2018///1212
KW  - Adenocarcinoma of Lung
KW  - drug therapy
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacology
KW  - Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
KW  - genetics
KW  - Calcium
KW  - metabolism
KW  - Cathepsins
KW  - antagonists & inhibitors
KW  - Cell Line, Tumor
KW  - Cysteine Proteinase Inhibitors
KW  - Exocytosis
KW  - Gene Expression Regulation, Neoplastic
KW  - Humans
KW  - Leucine
KW  - analogs & derivatives
KW  - Lung Neoplasms
KW  - Lysosomes
KW  - drug effects
KW  - Membrane Proteins
KW  - Mice
KW  - Neoplasm Metastasis
KW  - Nerve Tissue Proteins
KW  - Prognosis
KW  - Protein Isoforms
KW  - Proteolysis
KW  - Signal Transduction
KW  - Survival Analysis
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1038/s41467-018-05013-x
ER  -