TY - GEN AU - Wu,Lili AU - Han,Weichao AU - Chen,Yulian AU - Zhang,Tao AU - Liu,Junjin AU - Zhong,Shilong AU - Liu,Han AU - Han,Congcong AU - Zhang,Zhongyi AU - Liu,Shuwen AU - Tang,Lan TI - Gender Differences in the Hepatotoxicity and Toxicokinetics of Emodin: The Potential Mechanisms Mediated by UGT2B7 and MRP2 SN - 1543-8392 PY - 2019///0802 KW - Animals KW - Blotting, Western KW - Emodin KW - metabolism KW - Female KW - Genome-Wide Association Study KW - Genotype KW - Glucuronosyltransferase KW - genetics KW - HEK293 Cells KW - Hep G2 Cells KW - Humans KW - In Vitro Techniques KW - Kidney KW - Liver KW - Male KW - Multidrug Resistance-Associated Protein 2 KW - Multidrug Resistance-Associated Proteins KW - Polymorphism, Single Nucleotide KW - Quality Control KW - RNA, Small Interfering KW - Rats KW - Rats, Sprague-Dawley KW - Real-Time Polymerase Chain Reaction KW - Sex Factors KW - Toxicokinetics N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/acs.molpharmaceut.8b00387 ER -