TY - GEN AU - Li,Meng AU - Yu,Jason S L AU - Tilgner,Katarzyna AU - Ong,Swee Hoe AU - Koike-Yusa,Hiroko AU - Yusa,Kosuke TI - Genome-wide CRISPR-KO Screen Uncovers mTORC1-Mediated Gsk3 Regulation in Naive Pluripotency Maintenance and Dissolution SN - 2211-1247 PY - 2019///1107 KW - Animals KW - Cell Differentiation KW - genetics KW - Cell Self Renewal KW - Clustered Regularly Interspaced Short Palindromic Repeats KW - Gene Expression Regulation, Developmental KW - Gene Knockout Techniques KW - Genome KW - Glycogen Synthase Kinase 3 KW - metabolism KW - Mechanistic Target of Rapamycin Complex 1 KW - Mice KW - Mice, Knockout KW - Models, Biological KW - Mouse Embryonic Stem Cells KW - Phenotype KW - Pluripotent Stem Cells KW - cytology KW - Transcriptome N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.celrep.2018.06.027 ER -