TY - GEN AU - Zięba,Sebastian AU - Kowalik,Artur AU - Zalewski,Kamil AU - Rusetska,Natalia AU - Goryca,Krzysztof AU - Piaścik,Agata AU - Misiek,Marcin AU - Bakuła-Zalewska,Elwira AU - Kopczyński,Janusz AU - Kowalski,Kamil AU - Radziszewski,Jakub AU - Bidziński,Mariusz AU - Góźdź,Stanisław AU - Kowalewska,Magdalena TI - Somatic mutation profiling of vulvar cancer: Exploring therapeutic targets SN - 1095-6859 PY - 2018///1026 KW - AMP-Activated Protein Kinase Kinases KW - Adult KW - Aged KW - Aged, 80 and over KW - Antibiotics, Antineoplastic KW - pharmacology KW - Antineoplastic Agents KW - Benzamides KW - Carcinoma, Squamous Cell KW - genetics KW - Cell Line, Tumor KW - Cell Survival KW - drug effects KW - Class I Phosphatidylinositol 3-Kinases KW - Cyclin-Dependent Kinase Inhibitor p16 KW - Cyclin-Dependent Kinase Inhibitor p18 KW - DNA Mutational Analysis KW - DNA, Neoplasm KW - analysis KW - Disease-Free Survival KW - Everolimus KW - F-Box-WD Repeat-Containing Protein 7 KW - Female KW - GTP-Binding Protein alpha Subunits, Gq-G11 KW - High-Throughput Nucleotide Sequencing KW - Humans KW - Janus Kinase 3 KW - Middle Aged KW - Morpholines KW - Mutation KW - PTEN Phosphohydrolase KW - Papillomaviridae KW - Papillomavirus Infections KW - complications KW - Phosphatidylinositol 3-Kinase KW - metabolism KW - Protein Kinase Inhibitors KW - Protein Serine-Threonine Kinases KW - Proto-Oncogene Proteins c-akt KW - Proto-Oncogene Proteins p21(ras) KW - Pyrimidines KW - Receptor, Fibroblast Growth Factor, Type 3 KW - Signal Transduction KW - Sirolimus KW - Smad4 Protein KW - TOR Serine-Threonine Kinases KW - Tumor Suppressor Protein p53 KW - Vulvar Neoplasms KW - fms-Like Tyrosine Kinase 3 N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.ygyno.2018.06.026 ER -