Proteasome inhibition with bortezomib induces a therapeutically relevant depletion of plasma cells in SLE but does not target their precursors. [electronic resource]
- European journal of immunology 09 2018
- 1573-1579 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1521-4141
10.1002/eji.201847492 doi
Autoantibodies--blood Bortezomib--therapeutic use Complement System Proteins--metabolism Humans Immunoglobulins--blood Lupus Erythematosus, Systemic--drug therapy Lymphocyte Count Plasma Cells--cytology Precursor Cells, B-Lymphoid--cytology Precursor Cells, T-Lymphoid--cytology Proteasome Endopeptidase Complex--drug effects Proteasome Inhibitors--therapeutic use