TY - GEN AU - Viswanathan,Srinivas R AU - Nogueira,Marina F AU - Buss,Colin G AU - Krill-Burger,John M AU - Wawer,Mathias J AU - Malolepsza,Edyta AU - Berger,Ashton C AU - Choi,Peter S AU - Shih,Juliann AU - Taylor,Alison M AU - Tanenbaum,Benjamin AU - Pedamallu,Chandra Sekhar AU - Cherniack,Andrew D AU - Tamayo,Pablo AU - Strathdee,Craig A AU - Lage,Kasper AU - Carr,Steven A AU - Schenone,Monica AU - Bhatia,Sangeeta N AU - Vazquez,Francisca AU - Tsherniak,Aviad AU - Hahn,William C AU - Meyerson,Matthew TI - Genome-scale analysis identifies paralog lethality as a vulnerability of chromosome 1p loss in cancer SN - 1546-1718 PY - 2019///0424 KW - Animals KW - Cell Line, Tumor KW - Cell Nucleus KW - genetics KW - Chromosomes, Human, Pair 1 KW - Exons KW - Female KW - Gene Deletion KW - HEK293 Cells KW - Humans KW - Karyopherins KW - Mice KW - Mice, Nude KW - Neoplasms KW - Nuclear Proteins KW - RNA Splicing KW - RNA, Small Interfering N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1038/s41588-018-0155-3 ER -