TY  - GEN
AU  - Saenz-Ponce,Natalia
AU  - Pillay,Rachael
AU  - de Long,Lilia Merida
AU  - Kashyap,Trinayan
AU  - Argueta,Christian
AU  - Landesman,Yosef
AU  - Hazar-Rethinam,Mehlika
AU  - Boros,Samuel
AU  - Panizza,Benedict
AU  - Jacquemyn,Maarten
AU  - Daelemans,Dirk
AU  - Gannon,Orla M
AU  - Saunders,Nicholas A
TI  - Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas
SN  - 1946-6242
PY  - 2019///1004
KW  - Active Transport, Cell Nucleus
KW  - drug effects
KW  - Animals
KW  - Anthracyclines
KW  - pharmacology
KW  - Cell Line, Tumor
KW  - Cell Nucleus
KW  - Doxorubicin
KW  - Drug Resistance, Neoplasm
KW  - E2F1 Transcription Factor
KW  - metabolism
KW  - E2F7 Transcription Factor
KW  - Humans
KW  - Karyopherins
KW  - antagonists & inhibitors
KW  - Mice, Inbred NOD
KW  - Mice, SCID
KW  - Molecular Targeted Therapy
KW  - Phosphotransferases (Alcohol Group Acceptor)
KW  - Receptors, Cytoplasmic and Nuclear
KW  - Squamous Cell Carcinoma of Head and Neck
KW  - Exportin 1 Protein
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1126/scitranslmed.aar7223
ER  -