Saenz-Ponce, Natalia

Targeting the XPO1-dependent nuclear export of E2F7 reverses anthracycline resistance in head and neck squamous cell carcinomas. [electronic resource] - Science translational medicine 06 2018

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

1946-6242

10.1126/scitranslmed.aar7223 doi


Active Transport, Cell Nucleus--drug effects
Animals
Anthracyclines--pharmacology
Cell Line, Tumor
Cell Nucleus--drug effects
Doxorubicin--pharmacology
Drug Resistance, Neoplasm--drug effects
E2F1 Transcription Factor--metabolism
E2F7 Transcription Factor--metabolism
Humans
Karyopherins--antagonists & inhibitors
Mice, Inbred NOD
Mice, SCID
Molecular Targeted Therapy
Phosphotransferases (Alcohol Group Acceptor)--metabolism
Receptors, Cytoplasmic and Nuclear--antagonists & inhibitors
Squamous Cell Carcinoma of Head and Neck--metabolism
Exportin 1 Protein