TY  - GEN
AU  - Sehdev,Amikar
AU  - Karrison,Theodore
AU  - Zha,Yuanyuan
AU  - Janisch,Linda
AU  - Turcich,Michelle
AU  - Cohen,Ezra E W
AU  - Maitland,Michael
AU  - Polite,Blase N
AU  - Gajewski,Thomas F
AU  - Salgia,Ravi
AU  - Pinto,Navin
AU  - Bissonnette,Marc B
AU  - Fleming,Gini F
AU  - Ratain,Mark J
AU  - Sharma,Manish R
TI  - A pharmacodynamic study of sirolimus and metformin in patients with advanced solid tumors
SN  - 1432-0843
PY  - 2019///0801
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - Aged, 80 and over
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - administration & dosage
KW  - Biomarkers, Tumor
KW  - blood
KW  - Drug Synergism
KW  - Female
KW  - Humans
KW  - Leukocytes, Mononuclear
KW  - drug effects
KW  - Male
KW  - Metformin
KW  - Middle Aged
KW  - Neoplasms
KW  - Phosphorylation
KW  - Pilot Projects
KW  - Ribosomal Protein S6 Kinases, 70-kDa
KW  - Sirolimus
KW  - TOR Serine-Threonine Kinases
KW  - antagonists & inhibitors
KW  - Young Adult
N1  - Publication Type: Journal Article; Randomized Controlled Trial; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1007/s00280-018-3619-3
ER  -