TY  - GEN
AU  - Bapiro,Tashinga E
AU  - Sykes,Andy
AU  - Martin,Scott
AU  - Davies,Michael
AU  - Yates,James W T
AU  - Hoch,Matthias
AU  - Rollison,Helen E
AU  - Jones,Barry
TI  - Complete Substrate Inhibition of Cytochrome P450 2C8 by AZD9496, an Oral Selective Estrogen Receptor Degrader
SN  - 1521-009X
PY  - 2018///1211
KW  - Administration, Oral
KW  - Cinnamates
KW  - metabolism
KW  - Cytochrome P-450 CYP2C8
KW  - Cytochrome P-450 CYP2C8 Inhibitors
KW  - Dose-Response Relationship, Drug
KW  - Female
KW  - Humans
KW  - Indoles
KW  - Male
KW  - Microsomes, Liver
KW  - drug effects
KW  - Receptors, Estrogen
KW  - antagonists & inhibitors
KW  - Substrate Specificity
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1124/dmd.118.081539
ER  -