TY - GEN AU - Duong,Hong Quan AU - Nemazanyy,Ivan AU - Rambow,Florian AU - Tang,Seng Chuan AU - Delaunay,Sylvain AU - Tharun,Lars AU - Florin,Alexandra AU - Büttner,Reinhard AU - Vandaele,Daniel AU - Close,Pierre AU - Marine,Jean-Christophe AU - Shostak,Kateryna AU - Chariot,Alain TI - The Endosomal Protein CEMIP Links WNT Signaling to MEK1-ERK1/2 Activation in Selumetinib-Resistant Intestinal Organoids SN - 1538-7445 PY - 2019///0924 KW - Amino Acids KW - genetics KW - Benzimidazoles KW - pharmacology KW - Cell Line, Tumor KW - Colorectal Neoplasms KW - drug therapy KW - Drug Resistance, Neoplasm KW - Endosomes KW - metabolism KW - Gene Expression Regulation, Neoplastic KW - drug effects KW - Humans KW - Hyaluronoglucosaminidase KW - MAP Kinase Kinase 1 KW - antagonists & inhibitors KW - Mitogen-Activated Protein Kinase 1 KW - Mitogen-Activated Protein Kinase 3 KW - Organoids KW - Protein Kinase Inhibitors KW - Proteins KW - Proto-Oncogene Proteins B-raf KW - Proto-Oncogene Proteins c-fos KW - Proto-Oncogene Proteins c-myc KW - Wnt Signaling Pathway N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/0008-5472.CAN-17-3149 ER -