Dysfunction of HPV16-specific CD8+ T cells derived from oropharyngeal tumors is related to the expression of Tim-3 but not PD-1. [electronic resource]
- Oral oncology 07 2018
- 75-82 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1879-0593
10.1016/j.oraloncology.2018.05.010 doi
Adult Aged Antineoplastic Agents, Immunological--therapeutic use CD8-Positive T-Lymphocytes--immunology Cytokines--biosynthesis Female Hepatitis A Virus Cellular Receptor 2--metabolism Human papillomavirus 16--isolation & purification Humans Lymphocytes, Tumor-Infiltrating--immunology Male Middle Aged Nivolumab--therapeutic use Oropharyngeal Neoplasms--drug therapy Programmed Cell Death 1 Receptor--antagonists & inhibitors Tumor Escape