TY - GEN AU - Liu,Qing AU - Thoms,Julie A I AU - Nunez,Andrea C AU - Huang,Yizhou AU - Knezevic,Kathy AU - Packham,Deborah AU - Poulos,Rebecca C AU - Williams,Rachel AU - Beck,Dominik AU - Hawkins,Nicholas J AU - Ward,Robyn L AU - Wong,Jason W H AU - Hesson,Luke B AU - Sloane,Mathew A AU - Pimanda,John E TI - Disruption of a -35 kb Enhancer Impairs CTCF Binding and SN - 1557-3265 PY - 2019///1107 KW - Adult KW - Aged KW - Aged, 80 and over KW - CCCTC-Binding Factor KW - genetics KW - CRISPR-Cas Systems KW - Cell Line, Tumor KW - Colorectal Neoplasms KW - Colorectal Neoplasms, Hereditary Nonpolyposis KW - DNA Methylation KW - DNA Mismatch Repair KW - Enhancer Elements, Genetic KW - Female KW - Gene Expression Regulation, Neoplastic KW - Germ-Line Mutation KW - Humans KW - Male KW - Middle Aged KW - MutL Protein Homolog 1 KW - Promoter Regions, Genetic N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1158/1078-0432.CCR-17-3678 ER -