TY  - GEN
AU  - Decuyper,Lena
AU  - Deketelaere,Sari
AU  - Vanparys,Lore
AU  - Jukič,Marko
AU  - Sosič,Izidor
AU  - Sauvage,Eric
AU  - Amoroso,Ana Maria
AU  - Verlaine,Olivier
AU  - Joris,Bernard
AU  - Gobec,Stanislav
AU  - D'hooghe,Matthias
TI  - In Silico Design and Enantioselective Synthesis of Functionalized Monocyclic 3-Amino-1-carboxymethyl-β-lactams as Inhibitors of Penicillin-Binding Proteins of Resistant Bacteria
SN  - 1521-3765
PY  - 2018///1024
KW  - Amination
KW  - Anti-Bacterial Agents
KW  - chemical synthesis
KW  - Bacterial Infections
KW  - drug therapy
KW  - Computer Simulation
KW  - Computer-Aided Design
KW  - Drug Design
KW  - Drug Resistance, Bacterial
KW  - drug effects
KW  - Enterococcus faecium
KW  - Escherichia coli
KW  - Escherichia coli Infections
KW  - Gram-Positive Bacterial Infections
KW  - Humans
KW  - Molecular Docking Simulation
KW  - Penicillin-Binding Proteins
KW  - antagonists & inhibitors
KW  - beta-Lactams
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1002/chem.201801868
ER  -