Decuyper, Lena <br/><br/>
In Silico Design and Enantioselective Synthesis of Functionalized Monocyclic 3-Amino-1-carboxymethyl-β-lactams as Inhibitors of Penicillin-Binding Proteins of Resistant Bacteria.  [electronic resource] 

 -  Chemistry (Weinheim an der Bergstrasse, Germany)  Oct 2018 
 - 15254-15266 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1521-3765 
<br/><br/><label>Standard No.: </label>10.1002/chem.201801868  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amination<br/>Anti-Bacterial Agents--chemical synthesis<br/>Bacterial Infections--drug therapy<br/>Computer Simulation<br/>Computer-Aided Design<br/>Drug Design<br/>Drug Resistance, Bacterial--drug effects<br/>Enterococcus faecium--drug effects<br/>Escherichia coli--drug effects<br/>Escherichia coli Infections--drug therapy<br/>Gram-Positive Bacterial Infections--drug therapy<br/>Humans<br/>Molecular Docking Simulation<br/>Penicillin-Binding Proteins--antagonists & inhibitors<br/>beta-Lactams--chemical synthesis