Saei, Azad <br/><br/>
Loss of USP28-mediated BRAF degradation drives resistance to RAF cancer therapies.  [electronic resource] 

 -  The Journal of experimental medicine  07 2018 
 - 1913-1928 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1540-9538 
<br/><br/><label>Standard No.: </label>10.1084/jem.20171960  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Apoptosis--drug effects<br/>Cell Line, Tumor<br/>Down-Regulation<br/>Drug Resistance, Neoplasm<br/>F-Box-WD Repeat-Containing Protein 7--metabolism<br/>Gene Deletion<br/>Glycine--analogs & derivatives<br/>HEK293 Cells<br/>Humans<br/>MAP Kinase Signaling System<br/>Melanoma--drug therapy<br/>Mice<br/>Prognosis<br/>Protein Stability<br/>Proteolysis<br/>Proto-Oncogene Proteins B-raf--metabolism<br/>Sulfones--pharmacology<br/>Ubiquitin Thiolesterase--deficiency<br/>Vemurafenib--pharmacology