Enhanced mitochondrial DNA repair of the common disease-associated variant, Ser326Cys, of hOGG1 through small molecule intervention. [electronic resource]
- Free radical biology & medicine 08 2018
- 149-162 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural
1873-4596
10.1016/j.freeradbiomed.2018.05.094 doi
A549 Cells Animals Cells, Cultured DNA Damage DNA Glycosylases--genetics DNA Repair DNA, Mitochondrial--genetics Fibroblasts--cytology Herbicides--adverse effects Humans Mice Mice, Knockout Mitochondria--drug effects Mutation Oxidation-Reduction Oxidative Stress--drug effects Paraquat--adverse effects Reactive Oxygen Species--metabolism Serine--genetics Small Molecule Libraries--pharmacology