TY  - GEN
AU  - Lim,Ee Lyn
AU  - Cugliandolo,Fiorella M
AU  - Rosner,Dalya R
AU  - Gyori,David
AU  - Roychoudhuri,Rahul
AU  - Okkenhaug,Klaus
TI  - Phosphoinositide 3-kinase δ inhibition promotes antitumor responses but antagonizes checkpoint inhibitors
SN  - 2379-3708
PY  - 2019///1028
KW  - Animals
KW  - Antigens, Neoplasm
KW  - administration & dosage
KW  - Antineoplastic Agents, Immunological
KW  - pharmacology
KW  - Antineoplastic Combined Chemotherapy Protocols
KW  - Cancer Vaccines
KW  - Cell Line, Tumor
KW  - transplantation
KW  - Class I Phosphatidylinositol 3-Kinases
KW  - Costimulatory and Inhibitory T-Cell Receptors
KW  - antagonists & inhibitors
KW  - Diphtheria Toxin
KW  - Disease Models, Animal
KW  - Drug Interactions
KW  - Female
KW  - Humans
KW  - Lymphocyte Depletion
KW  - methods
KW  - Male
KW  - Mice
KW  - Neoplasms
KW  - drug therapy
KW  - Phosphatidylinositol 3-Kinases
KW  - immunology
KW  - Phosphoinositide-3 Kinase Inhibitors
KW  - Purines
KW  - Quinazolinones
KW  - Signal Transduction
KW  - drug effects
KW  - T-Lymphocytes, Cytotoxic
KW  - T-Lymphocytes, Regulatory
KW  - Treatment Outcome
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1172/jci.insight.120626
ER  -