TY - GEN AU - Guo,Chen AU - Chang,Thomas Ming Swi TI - Long term safety and immunological effects of a nanobiotherapeutic, bovine poly-[hemoglobin-catalase-superoxide dismutase-carbonic anhydrase], after four weekly 5% blood volume top-loading followed by a challenge of 30% exchange transfusion SN - 2169-141X PY - 2018///1018 KW - Animals KW - Arterial Pressure KW - drug effects KW - Blood Substitutes KW - adverse effects KW - Blood Transfusion KW - Blood Volume KW - Body Weight KW - Carbonic Anhydrases KW - chemistry KW - Catalase KW - Cattle KW - Complement C3a KW - metabolism KW - Hemoglobins KW - Humans KW - Immunoglobulin G KW - blood KW - Immunoglobulin M KW - Nanomedicine KW - methods KW - Protein Multimerization KW - Rats KW - Safety KW - Superoxide Dismutase N1 - Publication Type: Journal Article UR - https://doi.org/10.1080/21691401.2018.1476375 ER -