Combination of aptamer and drug for reversible anticoagulation in cardiopulmonary bypass. [electronic resource]
- Nature biotechnology 08 2018
- 606-613 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.
1546-1696
10.1038/nbt.4153 doi
Anticoagulants--administration & dosage Aptamers, Nucleotide--administration & dosage Cardiopulmonary Bypass--adverse effects Crystallography, X-Ray Drug Combinations Factor Xa--chemistry Factor Xa Inhibitors--administration & dosage Heparin--adverse effects Humans Postoperative Hemorrhage--drug therapy Protein Conformation--drug effects