Franqui-Machin, Reinaldo <br/><br/>
Destabilizing NEK2 overcomes resistance to proteasome inhibition in multiple myeloma.  [electronic resource] 

 -  The Journal of clinical investigation  07 2018 
 - 2877-2893 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1558-8238 
<br/><br/><label>Standard No.: </label>10.1172/JCI98765  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Bortezomib--pharmacology<br/>Cell Line, Tumor<br/>Cell Proliferation<br/>Drug Resistance, Neoplasm<br/>Gene Knockdown Techniques<br/>Glucuronidase--metabolism<br/>Humans<br/>Mice<br/>Mice, Inbred NOD<br/>Models, Biological<br/>Multiple Myeloma--drug therapy<br/>NF-kappa B--metabolism<br/>NIMA-Related Kinases--antagonists & inhibitors<br/>Prognosis<br/>Proteasome Endopeptidase Complex--metabolism<br/>Proteasome Inhibitors--pharmacology<br/>Protein Binding<br/>Protein Stability<br/>Signal Transduction<br/>Ubiquitin-Specific Peptidase 7--antagonists & inhibitors<br/>Ubiquitination<br/>Xenograft Model Antitumor Assays