TY  - GEN
AU  - Szot,Christopher
AU  - Saha,Saurabh
AU  - Zhang,Xiaoyan M
AU  - Zhu,Zhongyu
AU  - Hilton,Mary Beth
AU  - Morris,Karen
AU  - Seaman,Steven
AU  - Dunleavey,James M
AU  - Hsu,Kuo-Sheng
AU  - Yu,Guo-Jun
AU  - Morris,Holly
AU  - Swing,Deborah A
AU  - Haines,Diana C
AU  - Wang,Yanping
AU  - Hwang,Jennifer
AU  - Feng,Yang
AU  - Welsch,Dean
AU  - DeCrescenzo,Gary
AU  - Chaudhary,Amit
AU  - Zudaire,Enrique
AU  - Dimitrov,Dimiter S
AU  - St Croix,Brad
TI  - Tumor stroma-targeted antibody-drug conjugate triggers localized anticancer drug release
SN  - 1558-8238
PY  - 2019///0916
KW  - Animals
KW  - Antineoplastic Agents
KW  - pharmacokinetics
KW  - Biomarkers, Tumor
KW  - antagonists & inhibitors
KW  - Brentuximab Vedotin
KW  - Cell Line, Tumor
KW  - Female
KW  - Humans
KW  - Immunoconjugates
KW  - Male
KW  - Mice
KW  - Mice, Inbred C57BL
KW  - Mice, Knockout
KW  - Mice, Nude
KW  - Mice, SCID
KW  - Microfilament Proteins
KW  - Neoplasm Proteins
KW  - Neoplasms
KW  - drug therapy
KW  - Receptors, Cell Surface
KW  - Receptors, Peptide
KW  - Stromal Cells
KW  - drug effects
KW  - Tumor Microenvironment
KW  - Xenograft Model Antitumor Assays
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, N.I.H., Intramural; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1172/JCI120481
ER  -