Salgado-Freirķa, R <br/><br/>
Perfluorooctane sulfonate (PFOS) can alter the hypothalamic-pituitary-adrenal (HPA) axis activity by modifying CRF1 and glucocorticoid receptors.  [electronic resource] 

 -  Toxicology letters  Oct 2018 
 - 1-9 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1879-3169 
<br/><br/><label>Standard No.: </label>10.1016/j.toxlet.2018.05.025  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Adrenocorticotropic Hormone--blood<br/>Alkanesulfonic Acids--toxicity<br/>Animals<br/>Corticosterone--blood<br/>Corticotropin-Releasing Hormone--blood<br/>Dose-Response Relationship, Drug<br/>Down-Regulation<br/>Endocrine Disruptors--toxicity<br/>Fluorocarbons--toxicity<br/>Hypothalamo-Hypophyseal System--drug effects<br/>Male<br/>Pituitary-Adrenal System--drug effects<br/>RNA, Messenger--genetics<br/>Rats, Sprague-Dawley<br/>Receptors, Corticotropin-Releasing Hormone--drug effects<br/>Receptors, Glucocorticoid--drug effects<br/>Signal Transduction--drug effects<br/>Time Factors<br/>CRF Receptor, Type 1