TY  - GEN
AU  - Edwards,Emily S J
AU  - Bier,Julia
AU  - Cole,Theresa S
AU  - Wong,Melanie
AU  - Hsu,Peter
AU  - Berglund,Lucinda J
AU  - Boztug,Kaan
AU  - Lau,Anthony
AU  - Gostick,Emma
AU  - Price,David A
AU  - O'Sullivan,Michael
AU  - Meyts,Isabelle
AU  - Choo,Sharon
AU  - Gray,Paul
AU  - Holland,Steven M
AU  - Deenick,Elissa K
AU  - Uzel,Gulbu
AU  - Tangye,Stuart G
TI  - Activating PIK3CD mutations impair human cytotoxic lymphocyte differentiation and function and EBV immunity
SN  - 1097-6825
PY  - 2019///1112
KW  - Adolescent
KW  - Adult
KW  - Aged
KW  - B-Lymphocytes
KW  - immunology
KW  - CD8-Positive T-Lymphocytes
KW  - Cell Differentiation
KW  - genetics
KW  - Cellular Senescence
KW  - Child
KW  - Child, Preschool
KW  - Class I Phosphatidylinositol 3-Kinases
KW  - Epstein-Barr Virus Infections
KW  - Gain of Function Mutation
KW  - Genetic Diseases, Inborn
KW  - Herpesvirus 4, Human
KW  - Humans
KW  - Immunologic Surveillance
KW  - Killer Cells, Natural
KW  - Male
KW  - Middle Aged
N1  - Publication Type: Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1016/j.jaci.2018.04.030
ER  -