TY - GEN AU - Koenig,Mary Kay AU - Bell,Cynthia S AU - Hebert,Adelaide A AU - Roberson,Joan AU - Samuels,Joshua A AU - Slopis,John M AU - Tate,Patti AU - Northrup,Hope TI - Efficacy and Safety of Topical Rapamycin in Patients With Facial Angiofibromas Secondary to Tuberous Sclerosis Complex: The TREATMENT Randomized Clinical Trial SN - 2168-6084 PY - 2019///0916 KW - Administration, Cutaneous KW - Adolescent KW - Adult KW - Angiofibroma KW - drug therapy KW - Child KW - Child, Preschool KW - Double-Blind Method KW - Facial Neoplasms KW - Female KW - Humans KW - Immunosuppressive Agents KW - adverse effects KW - Male KW - Middle Aged KW - Prospective Studies KW - Quality of Life KW - Severity of Illness Index KW - Sirolimus KW - Skin Neoplasms KW - Time Factors KW - Tuberous Sclerosis KW - complications KW - Young Adult N1 - Publication Type: Journal Article; Multicenter Study; Randomized Controlled Trial; Research Support, U.S. Gov't, Non-P.H.S UR - https://doi.org/10.1001/jamadermatol.2018.0464 ER -