Wang, Zhuo

Cardiac fibrosis can be attenuated by blocking the activity of transglutaminase 2 using a selective small-molecule inhibitor. [electronic resource] - Cell death & disease 04 2018 - 613 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

2041-4889

10.1038/s41419-018-0573-2 doi


Angiotensin II
Animals
Collagen--metabolism
Dipeptides--metabolism
Disease Models, Animal
Fibrosis
GTP-Binding Proteins--antagonists & inhibitors
Human Umbilical Vein Endothelial Cells--drug effects
Humans
Mice
Myocardium--pathology
Myofibroblasts--drug effects
Protein Glutamine gamma Glutamyltransferase 2
Small Molecule Libraries--pharmacology
Transforming Growth Factor beta1--pharmacology
Transglutaminases--antagonists & inhibitors