MiR-29c reduces the cisplatin resistance of non-small cell lung cancer cells by negatively regulating the PI3K/Akt pathway. [electronic resource]
- Scientific reports 05 2018
- 8007 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
2045-2322
10.1038/s41598-018-26381-w doi
A549 Cells Adult Animals Carcinoma, Non-Small-Cell Lung--drug therapy Case-Control Studies Cisplatin--therapeutic use Down-Regulation--genetics Drug Resistance, Neoplasm--genetics Female Gene Expression Regulation, Neoplastic Genes, Tumor Suppressor--physiology Humans Lung Neoplasms--drug therapy Male Mice Mice, Nude MicroRNAs--physiology Phosphatidylinositol 3-Kinases--genetics Proto-Oncogene Proteins c-akt--genetics Signal Transduction--genetics Tumor Cells, Cultured Xenograft Model Antitumor Assays