TY  - GEN
AU  - Khalid,Samra
AU  - Hanif,Rumeza
AU  - Jabeen,Ishrat
AU  - Mansoor,Qaisar
AU  - Ismail,Muhammad
TI  - Pharmacophore modeling for identification of anti-IGF-1R drugs and in-vitro validation of fulvestrant as a potential inhibitor
SN  - 1932-6203
PY  - 2018///0806
KW  - Antineoplastic Agents
KW  - chemistry
KW  - Breast Neoplasms
KW  - drug therapy
KW  - Carrier Proteins
KW  - genetics
KW  - Databases, Pharmaceutical
KW  - Drug Evaluation, Preclinical
KW  - Estradiol
KW  - analogs & derivatives
KW  - Estrogen Receptor Antagonists
KW  - Estrogen Receptor alpha
KW  - Female
KW  - Fulvestrant
KW  - Gene Expression
KW  - drug effects
KW  - Humans
KW  - Insulin Receptor Substrate Proteins
KW  - Ligands
KW  - MCF-7 Cells
KW  - Membrane Proteins
KW  - Models, Chemical
KW  - Models, Molecular
KW  - Receptor, IGF Type 1
KW  - Receptors, Somatomedin
KW  - antagonists & inhibitors
KW  - Signal Transduction
KW  - User-Computer Interface
N1  - Publication Type: Journal Article; Validation Study
UR  - https://doi.org/10.1371/journal.pone.0196312
ER  -