Khalid, Samra <br/><br/>
Pharmacophore modeling for identification of anti-IGF-1R drugs and in-vitro validation of fulvestrant as a potential inhibitor.  [electronic resource] 

 -  PloS one  2018 
 - e0196312 p.  digital 
<br/><br/> Publication Type: Journal Article; Validation Study 
<br/><br/><label>ISSN: </label>1932-6203 
<br/><br/><label>Standard No.: </label>10.1371/journal.pone.0196312  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Antineoplastic Agents--chemistry<br/>Breast Neoplasms--drug therapy<br/>Carrier Proteins--genetics<br/>Databases, Pharmaceutical<br/>Drug Evaluation, Preclinical<br/>Estradiol--analogs & derivatives<br/>Estrogen Receptor Antagonists--chemistry<br/>Estrogen Receptor alpha--genetics<br/>Female<br/>Fulvestrant<br/>Gene Expression--drug effects<br/>Humans<br/>Insulin Receptor Substrate Proteins--genetics<br/>Ligands<br/>MCF-7 Cells<br/>Membrane Proteins<br/>Models, Chemical<br/>Models, Molecular<br/>Receptor, IGF Type 1<br/>Receptors, Somatomedin--antagonists & inhibitors<br/>Signal Transduction--drug effects<br/>User-Computer Interface