A transgenic mouse model for HLA-B*57:01-linked abacavir drug tolerance and reactivity. [electronic resource]
- The Journal of clinical investigation 07 2018
- 2819-2832 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Intramural; Research Support, U.S. Gov't, P.H.S.
1558-8238
10.1172/JCI99321 doi
Animals Anti-HIV Agents--adverse effects CD8-Positive T-Lymphocytes--immunology Dideoxynucleosides--adverse effects Disease Models, Animal Drug Hypersensitivity--genetics Drug Tolerance--genetics Drug-Related Side Effects and Adverse Reactions--genetics Female HLA-B Antigens--genetics Humans In Vitro Techniques Lymphocyte Activation--drug effects Male Mice Mice, Inbred C57BL Mice, Transgenic Reverse Transcriptase Inhibitors--adverse effects