Gao, Ming-Zhao <br/><br/>
Aberrant modulation of ribosomal protein S6 phosphorylation confers acquired resistance to MAPK pathway inhibitors in BRAF-mutant melanoma.  [electronic resource] 

 -  Acta pharmacologica Sinica  Feb 2019 
 - 268-278 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1745-7254 
<br/><br/><label>Standard No.: </label>10.1038/s41401-018-0020-z  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Cell Line, Tumor<br/>Drug Resistance, Neoplasm--drug effects<br/>Humans<br/>Imidazoles--pharmacology<br/>MAP Kinase Signaling System--drug effects<br/>Melanoma--drug therapy<br/>Mitogen-Activated Protein Kinase Kinases--antagonists & inhibitors<br/>Mutation<br/>Oximes--pharmacology<br/>Phosphorylation--drug effects<br/>Protein Kinase Inhibitors--pharmacology<br/>Proto-Oncogene Proteins B-raf--antagonists & inhibitors<br/>Pyridones--pharmacology<br/>Pyrimidinones--pharmacology<br/>Ribosomal Protein S6--metabolism<br/>TOR Serine-Threonine Kinases--antagonists & inhibitors