Jennings, Laura E <br/><br/>
BET bromodomain ligands: Probing the WPF shelf to improve BRD4 bromodomain affinity and metabolic stability.  [electronic resource] 

 -  Bioorganic & medicinal chemistry  07 2018 
 - 2937-2957 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>1464-3391 
<br/><br/><label>Standard No.: </label>10.1016/j.bmc.2018.05.003  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Biological Assay<br/>Blotting, Western<br/>Cell Cycle Proteins<br/>Crystallography, X-Ray<br/>Drug Stability<br/>Heterocyclic Compounds, 4 or More Rings--chemistry<br/>Humans<br/>Inhibitory Concentration 50<br/>Ligands<br/>Luciferases--chemistry<br/>MCF-7 Cells<br/>Molecular Dynamics Simulation<br/>Molecular Structure<br/>Nuclear Proteins--chemistry<br/>Structure-Activity Relationship<br/>Transcription Factors--chemistry