TY - GEN AU - Xue,Xiaoqian AU - Zhang,Yan AU - Wang,Chao AU - Zhang,Maofeng AU - Xiang,Qiuping AU - Wang,Junjian AU - Wang,Anhui AU - Li,Chenchang AU - Zhang,Cheng AU - Zou,Lingjiao AU - Wang,Rui AU - Wu,Shuang AU - Lu,Yongzhi AU - Chen,Hongwu AU - Ding,Ke AU - Li,Guohui AU - Xu,Yong TI - Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer SN - 1768-3254 PY - 2018///0619 KW - Animals KW - Antineoplastic Agents KW - chemical synthesis KW - Benzoxazines KW - chemistry KW - Cell Movement KW - drug effects KW - Cell Proliferation KW - Cell Survival KW - Dose-Response Relationship, Drug KW - Drug Screening Assays, Antitumor KW - Humans KW - Isoxazoles KW - Male KW - Molecular Structure KW - Prostatic Neoplasms, Castration-Resistant KW - drug therapy KW - Proteins KW - antagonists & inhibitors KW - Rats KW - Rats, Sprague-Dawley KW - Structure-Activity Relationship KW - Tumor Cells, Cultured N1 - Publication Type: Journal Article UR - https://doi.org/10.1016/j.ejmech.2018.04.034 ER -