Xue, Xiaoqian <br/><br/>
Benzoxazinone-containing 3,5-dimethylisoxazole derivatives as BET bromodomain inhibitors for treatment of castration-resistant prostate cancer.  [electronic resource] 

 -  European journal of medicinal chemistry  May 2018 
 - 542-559 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>1768-3254 
<br/><br/><label>Standard No.: </label>10.1016/j.ejmech.2018.04.034  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--chemical synthesis<br/>Benzoxazines--chemistry<br/>Cell Movement--drug effects<br/>Cell Proliferation--drug effects<br/>Cell Survival--drug effects<br/>Dose-Response Relationship, Drug<br/>Drug Screening Assays, Antitumor<br/>Humans<br/>Isoxazoles--chemistry<br/>Male<br/>Molecular Structure<br/>Prostatic Neoplasms, Castration-Resistant--drug therapy<br/>Proteins--antagonists & inhibitors<br/>Rats<br/>Rats, Sprague-Dawley<br/>Structure-Activity Relationship<br/>Tumor Cells, Cultured