Figueroa, Isabel

Prediction of non-linear pharmacokinetics in humans of an antibody-drug conjugate (ADC) when evaluation of higher doses in animals is limited by tolerability: Case study with an anti-CD33 ADC. [electronic resource] - mAbs 07 2018 - 738-750 p. digital

Publication Type: Journal Article

1942-0870

10.1080/19420862.2018.1465160 doi


Algorithms
Animals
Antibodies, Monoclonal--immunology
Cell Line, Tumor
HEK293 Cells
Humans
Immunoconjugates--immunology
Macaca fascicularis
Models, Biological
Prospective Studies
Sialic Acid Binding Ig-like Lectin 3--immunology
Species Specificity